Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 12019
LigandPNGBDBM670766(4-[2-[(3R,4R)-3-acetamido-1-[7-(ethylamino)-5-fluo...)
Affinity DataIC50: 9nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670723(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 10nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670711(2-chloro-4-[[(3R)-1-[(3R)-7-(ethylamino)-5-fluoro-...)
Affinity DataIC50: 15nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670749(2-cyano-N-[(3R)-1-[3-ethyl-7-(ethylamino)-5-fluoro...)
Affinity DataIC50: 15nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670759(5-[[(3S,4S)-1-[3-ethyl-7-(ethylamino)-5-fluoro-2-o...)
Affinity DataIC50: 16nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670769((3R,4R)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-2...)
Affinity DataIC50: 17nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670724(6-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 17nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670764(1-cyano-N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-me...)
Affinity DataIC50: 18nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670770(US20240140933, Example 60B | (3R,4R)-1-[(3R)-7-(et...)
Affinity DataIC50: 21nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670773(US20240140933, Example 63A | (3S,4S)-1-[(3R)-7-(et...)
Affinity DataIC50: 22nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
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LigandPNGBDBM670755(5-[[(3R,5R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 26nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670756(5-[[(3R,5S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 28nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670727(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 29nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670763(N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-o...)
Affinity DataIC50: 32nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670753(4-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 32nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670760(5-[[(3S,4S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 33nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670767(4-[2-[(3R,4R)-3-acetamido-1-[7-(ethylamino)-5-fluo...)
Affinity DataIC50: 34nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670750(2-(2-chloroacetyl)-N-[(3R)-1-[7-(ethylamino)-5-flu...)
Affinity DataIC50: 34nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670712(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 35nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670719(4-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 35nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670729(7-(ethylamino)-5-fluoro-3-[(3R)-3-[4-(2-hydroxyace...)
Affinity DataIC50: 36nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670734(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 36nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670761(5-[[(3S,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 40nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670752(3-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 41nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670754(7-(ethylamino)-5-fluoro-3-[(3R)-3-[(3-fluorosulfon...)
Affinity DataIC50: 43nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670757(5-[[(3R,5S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 45nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670762(N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-o...)
Affinity DataIC50: 47nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670721(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 47nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670771(US20240140933, Example 61B | (3R,4R)-1-[(3R)-7-(et...)
Affinity DataIC50: 47nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670718(4-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 54nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670732(3-chloro-5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-met...)
Affinity DataIC50: 54nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670768(N-[(3R,4R)-4-[2-(4-cyanophenoxy)phenyl]-1-[7-(ethy...)
Affinity DataIC50: 55nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670758(5-[[(3S,4S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 59nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670748(1-cyano-N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methy...)
Affinity DataIC50: 59nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670738(4-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 65nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670745(N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-...)
Affinity DataIC50: 65nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670751(N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-...)
Affinity DataIC50: 66nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670744(7-(ethylamino)-5-fluoro-3-methyl-3-[(3R)-3-(4-viny...)
Affinity DataIC50: 68nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670739(6-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 75nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670765(5-[[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-...)
Affinity DataIC50: 76nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670772(US20240140933, Example 62B | (3R,4R)-N-benzyl-1-[(...)
Affinity DataIC50: 76nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670713(4-[[(3R)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-...)
Affinity DataIC50: 77nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670730(7-(ethylamino)-5-fluoro-3-methyl-3-[(3R)-3-[(6-met...)
Affinity DataIC50: 82nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670747(2-cyano-N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methy...)
Affinity DataIC50: 86nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670731(7-(ethylamino)-5-fluoro-3-[(3R)-3-[(6-hydroxy-3-py...)
Affinity DataIC50: 93nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670746(N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-...)
Affinity DataIC50: 101nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670715(4-[[(3S)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 108nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670714(4-[[(3R)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-...)
Affinity DataIC50: 109nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670726(6-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 115nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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LigandPNGBDBM670733(5-[[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo...)
Affinity DataIC50: 116nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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