Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 12078
TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676700((R)-2-fluoro-4-(3-(methyl(7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50: 2.51nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676761(5-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4- | US202...)
Affinity DataIC50: 12.6nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676769((R)-5-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4- | U...)
Affinity DataIC50: 12.6nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676762((R)-6-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4- | U...)
Affinity DataIC50: 20nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676764(methyl 2-(4-chloro-2-fluorophenyl)-2-(3-(methyl(7H...)
Affinity DataIC50: 25.1nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676768((R)-4-fluoro-2-(3-(methyl(7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50: 25.1nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676763(7-((1-(4-cyano-3-fluorophenyl)pyrrolidin-3- | US20...)
Affinity DataIC50: 100nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676766(ethyl 7-((1-(4-cyano-3-fluorophenyl)pyrrolidin-3- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676765(2-(4-chloro-2-fluorophenyl)-2-(3-(methyl(7H-pyrrol...)
Affinity DataIC50: 5.01E+3nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676767(7-((1-(4-cyano-3-fluorophenyl)pyrrolidin-3- | US20...)
Affinity DataIC50: 5.01E+3nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent