Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 12109
TargetTyrosine-protein kinase BTK(Human)
Jumbo Drug Bank Co.

US Patent
LigandPNGBDBM679455(US20240182466, Compound 1B)
Affinity DataIC50: 2.16nMAssay Description:Experimental example 1: EGFR, ITK, TEC, and BTK kinase test.1. Reaction condition:Buffer condition: 20 mM HEPES(pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
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TargetTyrosine-protein kinase Tec(Human)
Jumbo Drug Bank Co.

US Patent
LigandPNGBDBM679455(US20240182466, Compound 1B)
Affinity DataIC50: 74.8nMAssay Description:Experimental example 1: EGFR, ITK, TEC, and BTK kinase test.1. Reaction condition:Buffer condition: 20 mM HEPES(pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
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TargetEpidermal growth factor receptor(Human)
Jumbo Drug Bank Co.

US Patent
LigandPNGBDBM679455(US20240182466, Compound 1B)
Affinity DataIC50: 829nMAssay Description:Experimental example 1: EGFR, ITK, TEC, and BTK kinase test.1. Reaction condition:Buffer condition: 20 mM HEPES(pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
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TargetTyrosine-protein kinase ITK/TSK(Human)
Jumbo Drug Bank Co.

US Patent
LigandPNGBDBM679455(US20240182466, Compound 1B)
Affinity DataIC50: 5.43E+3nMAssay Description:Experimental example 1: EGFR, ITK, TEC, and BTK kinase test.1. Reaction condition:Buffer condition: 20 mM HEPES(pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
Go to US Patent