Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 12145
TargetCytochrome P450 3A4(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682655(US20240208932, Compound 43 | (S)-N-(4-((1R,3R)-7-e...)
Affinity DataIC50: 1.27E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682656(WO2021228210, Compound 4 | (S)-N-(3,5-Difluoro-4-(...)
Affinity DataIC50: 1.28E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682656(WO2021228210, Compound 4 | (S)-N-(3,5-Difluoro-4-(...)
Affinity DataIC50: 1.38E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682656(WO2021228210, Compound 4 | (S)-N-(3,5-Difluoro-4-(...)
Affinity DataIC50: 1.56E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682656(WO2021228210, Compound 4 | (S)-N-(3,5-Difluoro-4-(...)
Affinity DataIC50: 1.56E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682654(US20240208932, Compound 18 | (S)-N-(3,5-difluoro-4...)
Affinity DataIC50: 1.57E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682653(US20240208932, Compound 32)
Affinity DataIC50: 1.89E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682656(WO2021228210, Compound 4 | (S)-N-(3,5-Difluoro-4-(...)
Affinity DataIC50: 1.91E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682653(US20240208932, Compound 32)
Affinity DataIC50: 1.95E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682654(US20240208932, Compound 18 | (S)-N-(3,5-difluoro-4...)
Affinity DataIC50: 2.00E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682655(US20240208932, Compound 43 | (S)-N-(4-((1R,3R)-7-e...)
Affinity DataIC50: 2.15E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682653(US20240208932, Compound 32)
Affinity DataIC50: 2.34E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682654(US20240208932, Compound 18 | (S)-N-(3,5-difluoro-4...)
Affinity DataIC50: 3.41E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682655(US20240208932, Compound 43 | (S)-N-(4-((1R,3R)-7-e...)
Affinity DataIC50: 4.16E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682655(US20240208932, Compound 43 | (S)-N-(4-((1R,3R)-7-e...)
Affinity DataIC50: 4.28E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682655(US20240208932, Compound 43 | (S)-N-(4-((1R,3R)-7-e...)
Affinity DataIC50: 5.00E+4nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682653(US20240208932, Compound 32)
Affinity DataIC50: 1.00E+5nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM682654(US20240208932, Compound 18 | (S)-N-(3,5-difluoro-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:The purpose of this study was to evaluate the effect of the test compound on the activity of five isoenzymes (CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent