Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 12290
TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693801(1-(5-(((1S,2S)-2-(3-(4,4- difluorocyclohexyl)azeti...)
Affinity DataEC50:  6.21E+3nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693813(3-(5-(((1S,2S)-2-(3-cyclobutylazetidin- 1-yl)cyclo...)
Affinity DataEC50:  18nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693812(3-(5-(((1S,2S)-2-(3- cyclopropylazetidin-1- yl)cyc...)
Affinity DataEC50:  16nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693811(3-(5-(((1S,2S)-2-(3-cyclobutylazetidin- 1-yl)cyclo...)
Affinity DataEC50:  28nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693810(3-(5-(((1S,2S)-2-(3- cyclopropylazetidin-1- yl)cyc...)
Affinity DataEC50:  49nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693809(1-(1-((1S,2S)-2-((2-(2,6- dioxopiperidin-3-yl)-1-o...)
Affinity DataEC50:  28nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693808(3-(5-(((1S,2S)-2-(3- cyclopropylazetidin-1- yl)cyc...)
Affinity DataEC50:  22nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693807(3-(5-(((1S,2S)-2-(3-(4- (difluoromethoxy)cyclohexy...)
Affinity DataEC50:  1nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693806(3-(5-(((1S,2S)-2-(3-(3,3- difluorocyclohexyl)azeti...)
Affinity DataEC50:  4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693805(3-(5-(((1S,2S)-2-(3-(4- ethoxycyclohexyl)azetidin-...)
Affinity DataEC50:  1nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693804(3-(5-(((1S,2S)-2-(3-(3,3- difluorocyclobutyl)azeti...)
Affinity DataEC50:  12nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693802(3-(5-(((1S,2S)-2-(3-((cis)-4- isopropoxycyclohexyl...)
Affinity DataEC50:  1nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693802(3-(5-(((1S,2S)-2-(3-((cis)-4- isopropoxycyclohexyl...)
Affinity DataEC50:  2nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693788(3-(5-(((1S,2S)-2-(3- cyclohexylazetidin-1- yl)cycl...)
Affinity DataEC50:  3nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693800(1-(5-(((1S,2S)-2-(3-(4,4- difluorocyclohexyl)azeti...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693799(3-(5-(((1S,2S)-2-(3-(4,4- difluorocyclohexyl)azeti...)
Affinity DataEC50:  5nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693798(1-(5-(((1S,2S)-2-(3-((cis)-4- methoxycyclohexyl)az...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693797(1-(5-(((1S,2S)-2-(3-((cis)-4- methoxycyclohexyl)az...)
Affinity DataEC50: >1.00E+4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693795(US20240287037, Example 9 | US20240287037, Example ...)
Affinity DataEC50:  2nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693795(US20240287037, Example 9 | US20240287037, Example ...)
Affinity DataEC50:  3nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693793(US20240287037, Example 7 | 3-(5-(((1S,2S)-2-(3-((c...)
Affinity DataEC50:  4nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693793(US20240287037, Example 7 | 3-(5-(((1S,2S)-2-(3-((c...)
Affinity DataEC50:  2nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693792(3-(5-(((1S,2S)-2-(3- cyclopentylazetidin-1- yl)cyc...)
Affinity DataEC50:  5nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693791(3-(5-(((1S,2S)-2-(3-cyclobutylazetidin- 1-yl)cyclo...)
Affinity DataEC50:  9nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693790(3-(5-(((1S,2S)-2-(3- cyclopropylazetidin-1- yl)cyc...)
Affinity DataEC50:  9nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent

TargetProtein cereblon(Human)
Plexium

US Patent
LigandPNGBDBM693789(3-(5-(((1S,2S)-2-(3-(4,4- difluorocyclohexyl)azeti...)
Affinity DataEC50:  2nMAssay Description:Cereblon target engagement was monitored by Bioluminescence Resonance Energy Transfer (BRET) in transfected HEK-293T cells using the NanoBRET TE Intr...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent