Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 12386
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699777(US20240335427, Compound 8)
Affinity DataIC50: 12nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699772(US20240335427, Compound 3)
Affinity DataIC50: 28nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699773(US20240335427, Compound 4)
Affinity DataIC50: 45nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50590283(CHEMBL5169766 | US20230303547, Reference Example D...)
Affinity DataIC50: 73nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699774(US20240335427, Compound 5)
Affinity DataIC50: 74nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699775(US20240335427, Compound 6)
Affinity DataIC50: 82nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699808(US20240335427, Compound 38)
Affinity DataIC50: 89nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699789(US20240335427, Compound 19)
Affinity DataIC50: 90nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699776(US20240335427, Compound 7)
Affinity DataIC50: 95nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699777(US20240335427, Compound 8)
Affinity DataIC50: 99nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699796(US20240335427, Compound 26)
Affinity DataIC50: 100nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699782(US20240335427, Compound 12)
Affinity DataIC50: 100nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699802(US20240335427, Compound 32)
Affinity DataIC50: 104nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699778(US20240335427, Compound 9)
Affinity DataIC50: 150nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699798(US20240335427, Compound 28)
Affinity DataIC50: 155nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699780(US20240335427, Compound 10)
Affinity DataIC50: 160nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699781(US20240335427, Compound 11)
Affinity DataIC50: 160nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699779(US20240335427, Compound 2)
Affinity DataIC50: 160nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699782(US20240335427, Compound 12)
Affinity DataIC50: 244nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699783(US20240335427, Compound 13)
Affinity DataIC50: 260nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699784(US20240335427, Compound 14)
Affinity DataIC50: 270nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699785(US20240335427, Compound 15)
Affinity DataIC50: 288nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699786(US20240335427, Compound 16)
Affinity DataIC50: 305nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699787(US20240335427, Compound 17)
Affinity DataIC50: 370nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699788(US20240335427, Compound 18)
Affinity DataIC50: 380nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699789(US20240335427, Compound 19)
Affinity DataIC50: 420nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699805(US20240335427, Compound 35)
Affinity DataIC50: 420nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699790(US20240335427, Compound 20)
Affinity DataIC50: 430nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699791(US20240335427, Compound 21)
Affinity DataIC50: 460nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699792(US20240335427, Compound 22)
Affinity DataIC50: 520nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50590283(CHEMBL5169766 | US20230303547, Reference Example D...)
Affinity DataIC50: 660nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699794(US20240335427, Compound 24)
Affinity DataIC50: 690nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699795(US20240335427, Compound 25)
Affinity DataIC50: 931nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699812(US20240335427, Compound 42)
Affinity DataIC50: 1.08E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699796(US20240335427, Compound 26)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699797(US20240335427, Compound 27)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699798(US20240335427, Compound 28)
Affinity DataIC50: 1.22E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699799(US20240335427, Compound 29)
Affinity DataIC50: 1.24E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699817(US20240335427, Compound 47)
Affinity DataIC50: 1.29E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699806(US20240335427, Compound 36)
Affinity DataIC50: 1.34E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699800(US20240335427, Compound 30)
Affinity DataIC50: 1.37E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699801(US20240335427, Compound 31)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699802(US20240335427, Compound 32)
Affinity DataIC50: 1.48E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699803(US20240335427, Compound 33)
Affinity DataIC50: 1.83E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699794(US20240335427, Compound 24)
Affinity DataIC50: 1.85E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699803(US20240335427, Compound 33)
Affinity DataIC50: 1.95E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699785(US20240335427, Compound 15)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699799(US20240335427, Compound 29)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699790(US20240335427, Compound 20)
Affinity DataIC50: 2.06E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetJosephin-1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445205(US10669234, Example 144 | (S)-1-cyano-N-(4-(6-cyan...)
Affinity DataIC50: 2.13E+3nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

Displayed 1 to 50 (of 74 total ) | Next | Last >>
Jump to: