Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 12406
TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700982(Methyl (S)-(5-((2-amino-2,4-dimethylpent-4-en-1-yl...)
Affinity DataIC50: 5.74nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700998(N-(4-(4-(((2S)-2-amino-4,5-dihydroxy-2,4-dimethylp...)
Affinity DataIC50: 5.96nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700978((S)-N-(4-(4-((2-amino-2,4-dimethylpent-4-en-1-yl)o...)
Affinity DataIC50: 6.37nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM701000(US20240343720, Compound 30)
Affinity DataIC50: 9.08nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700976(1-((2',6-bis(difluoromethyl)-[2,4'-bipyridin]-5-yl...)
Affinity DataIC50: 9.29nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700988((S)-methyl-(6-((2-amino-4-fluoro-2,4-dimethylpenty...)
Affinity DataIC50: 9.55nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700983((S)-N-(4-(4-((2-amino-2,4-dimethylpent-4-en-1-yl)o...)
Affinity DataIC50: 10.6nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM701001(US20240343720, Compound 31)
Affinity DataIC50: 10.9nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700977(US20240343720, Compound 3)
Affinity DataIC50: 10.9nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700999(US20240343720, Compound 29)
Affinity DataIC50: 11nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700979((S)-N-(4-(4-((2-amino-4-fluoro-2,4-dimethylpentyl)...)
Affinity DataIC50: 11nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700996((S)-1-((2',6-bis(difluoromethyl)-[2,4'-bipyridin]-...)
Affinity DataIC50: 11nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700981(Methyl (S)-(5-((2-amino-2,4-dimethylpent-4-en-1-yl...)
Affinity DataIC50: 11.5nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700995((1R,2R)-N-(4-(4-(((S)-2-amino-2,4-dimethylpent-4-e...)
Affinity DataIC50: 11.9nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700984((S)-N-(4-(4-((2-amino-4-fluoro-2,4-dimethylpentyl)...)
Affinity DataIC50: 12.6nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700991(Methyl (S)-(5-((2-amino-4-fluoro-2,4-dimethylpenty...)
Affinity DataIC50: 13.7nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700980(US20240343720, Compound 7)
Affinity DataIC50: 13.8nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700975(1-((2',5-bis(difluoromethyl)-[3,4'-bipyridin]-6-yl...)
Affinity DataIC50: 14.7nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700990(Methyl (S)-(5-((2-amino-4-fluoro-2,4-dimethylpenty...)
Affinity DataIC50: 16.1nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700985((S)-N-(5-((2-amino-2,4-dimethylpent-4-en-1-yl)oxy)...)
Affinity DataIC50: 19.8nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700986((S)-N-(5-((2-amino-4-fluoro-2,4-dimethylpentyl)oxy...)
Affinity DataIC50: 22.3nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700994((S)-N-(4-(4-((2-amino-2,4-dimethylpent-4-en-1-yl)o...)
Affinity DataIC50: 22.5nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700987((S)-methyl-(6-((2-amino-2,4-dimethylpent-4-en-1-yl...)
Affinity DataIC50: 26.8nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700992(1-(((2',6-bis(difluoromethyl)-[2,4'-bipyridin]-5-y...)
Affinity DataIC50: 32.1nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700989(Methyl (S)-(5-((2-amino-4-fluoro-2,4-dimethylpenty...)
Affinity DataIC50: 37.7nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700993((S)-5-(2-acetamidopyridin-4-yl)-2-((2-amino-2,4-di...)
Affinity DataIC50: 38.6nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
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TargetAP2-associated protein kinase 1(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandPNGBDBM700997(Methyl (5-((2-amino-2,4-dimethylpent-3-en-1-yl)oxy...)
Affinity DataIC50: 43.1nMAssay Description:Compound stock solution (concentration: 10 mM, dissolved in DMSO) was diluted with DMSO to 0.2 mM and then diluted with DMSO in 5-fold gradient to ob...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
Go to US Patent