Compile Data Set for Download or QSAR
Report error Found 415 Enz. Inhib. hit(s) with all data for entry = 12492
TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706571(US20240383915, Example 100a)
Affinity DataIC50: 0.0300nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706571(US20240383915, Example 100a)
Affinity DataIC50: 0.0300nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706507(US20240383915, Example 48)
Affinity DataIC50: 0.0400nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706612(US20240383915, Example 133c)
Affinity DataIC50: 0.0500nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706594(US20240383915, Example 119)
Affinity DataIC50: 0.0500nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706535(US20240383915, Example 75a)
Affinity DataIC50: 0.0500nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706551(US20240383915, Example 88)
Affinity DataIC50: 0.0500nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706526(US20240383915, Example 66a)
Affinity DataIC50: 0.0500nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706591(US20240383915, Example 116)
Affinity DataIC50: 0.0520nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706539(US20240383915, Example 78)
Affinity DataIC50: 0.0600nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706626(US20240383915, Example 147)
Affinity DataIC50: 0.0600nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706593(US20240383915, Example 118)
Affinity DataIC50: 0.0600nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706609(US20240383915, Example 130a)
Affinity DataIC50: 0.0600nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706573(US20240383915, Example 101)
Affinity DataIC50: 0.0600nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706582(US20240383915, Example 108a)
Affinity DataIC50: 0.0600nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706573(US20240383915, Example 101)
Affinity DataIC50: 0.0620nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706556(US20240383915, Example 92a)
Affinity DataIC50: 0.0650nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706535(US20240383915, Example 75a)
Affinity DataIC50: 0.0660nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706542(US20240383915, Example 81)
Affinity DataIC50: 0.0660nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706542(US20240383915, Example 81)
Affinity DataIC50: 0.0670nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706604(US20240383915, Example 127)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706562(US20240383915, Example 94)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706595(US20240383915, Example 120a)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706561(US20240383915, Example 93d)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706569(US20240383915, Example 99a)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706609(US20240383915, Example 130a)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706560(US20240383915, Example 93c)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706616(US20240383915, Example 137)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706556(US20240383915, Example 92a)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706597(US20240383915, Example 121)
Affinity DataIC50: 0.0700nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706591(US20240383915, Example 116)
Affinity DataIC50: 0.0740nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706570(US20240383915, Example 99b)
Affinity DataIC50: 0.0750nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706552(US20240383915, Example 89)
Affinity DataIC50: 0.0750nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706596(US20240383915, Example 120b)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706570(US20240383915, Example 99b)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706579(US20240383915, Example 105a)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706618(US20240383915, Example 139)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706592(US20240383915, Example 117)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706566(US20240383915, Example 97)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706647(US20240383915, Example 175)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706565(US20240383915, Example 96)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706614(US20240383915, Example 135)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706613(US20240383915, Example 134)
Affinity DataIC50: 0.0800nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706561(US20240383915, Example 93d)
Affinity DataIC50: 0.0850nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706549(US20240383915, Example 87a)
Affinity DataIC50: 0.0870nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706550(US20240383915, Example 87b)
Affinity DataIC50: 0.0890nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas(Human)
Genentech

US Patent
LigandPNGBDBM706604(US20240383915, Example 127)
Affinity DataIC50: 0.0890nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706547(US20240383915, Example 85)
Affinity DataIC50: 0.0900nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706563(US20240383915, Example 95a)
Affinity DataIC50: 0.0900nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
Genentech

US Patent
LigandPNGBDBM706587(US20240383915, Example 113a)
Affinity DataIC50: 0.0900nMAssay Description:KRAS Biochemical Assay—BODIPY-GDP Exchange TR-FRET. Biochemical compound potencies were assessed by evaluating inhibition of SOS1-mediated nucleotide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent

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