Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 12527
TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM4375(3,4-Dihydroxycinnamate, XVII | cid_689043 | Caffei...)
Affinity DataIC50: 100nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM500011(US11021454, Compound D-dopa | US20240415800, Compo...)
Affinity DataIC50: 200nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM500011(US11021454, Compound D-dopa | US20240415800, Compo...)
Affinity DataIC50: 200nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM4375(3,4-Dihydroxycinnamate, XVII | cid_689043 | Caffei...)
Affinity DataIC50: 300nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM60928(L-DOPA | dihydroxyphenylalanine | BDBM50130192 | L...)
Affinity DataIC50: 400nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM60928(L-DOPA | dihydroxyphenylalanine | BDBM50130192 | L...)
Affinity DataIC50: 600nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM41957(3-[3,4-bis(oxidanyl)phenyl]propanoic acid | 3-(3,4...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM707655(US20240415800, Compound 2-6)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM18129((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM707652(US20240415800, Compound 2-3)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM707653(US20240415800, Compound 2-4)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent

TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM48449(SMR000059170 | MLS000028644 | cid_38853 | 3-(3,4-D...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
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TargetGlutamate carboxypeptidase 2(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition potencies against GCPII (IC50 values) were determined using previously described methods with minor modification. Rojas et al., 2002. Brie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent