Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 12678
Affinity DataKi: 0.100nMAssay Description:Aliquoted membrane preparations were incubated with 0.7 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates ...More data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Aliquoted membrane preparations were incubated with 0.7 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates ...More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Aliquoted membrane preparations were incubated with 0.7 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates ...More data for this Ligand-Target Pair
Affinity DataKi: 0.182nMAssay Description:Aliquoted membrane preparations were incubated with 0.7 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates ...More data for this Ligand-Target Pair
Affinity DataKi: 0.309nMAssay Description:Compounds were diluted in DMSO and binding buffer (containing 50 mM Tris, 5 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 120 mM NaCl, 1 mM EDTA) and 50 μL of each...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Aliquoted membrane preparations were incubated with 0.16 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates...More data for this Ligand-Target Pair
Affinity DataKi: 0.708nMAssay Description:Compounds were diluted in DMSO and binding buffer (containing 50 mM Tris, 5 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 120 mM NaCl, 1 mM EDTA) and 50 μL of each...More data for this Ligand-Target Pair
Affinity DataEC50: 0.724nMAssay Description:PathHunter CHO-K1 cells expressing tagged human D2L receptors and tagged β-arrestin-2 (Eurofins DiscoverX, Fremont, CA, USA) were seeded into 96-well...More data for this Ligand-Target Pair
Affinity DataKi: 0.871nMAssay Description:Aliquoted membrane preparations were incubated with 0.16 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates...More data for this Ligand-Target Pair
Affinity DataKi: 1.02nMAssay Description:Compounds were diluted in DMSO and binding buffer (containing 50 mM Tris, 5 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 120 mM NaCl, 1 mM EDTA) and 50 μL of each...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:PathHunter CHO-K1 cells expressing tagged human D2L receptors and tagged β-arrestin-2 (Eurofins DiscoverX, Fremont, CA, USA) were seeded into 96-well...More data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Test compounds were diluted serially in DMSO and subsequently diluted to 5% DMSO (v/w) in binding buffer (50 mM Tris, 5 mM MgCl2, 5 mM KCl, 1 mM CaCl...More data for this Ligand-Target Pair
Affinity DataKi: 1.17nMAssay Description:Aliquoted membrane preparations were incubated with 0.16 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates...More data for this Ligand-Target Pair
Affinity DataKi: 1.17nMAssay Description:Aliquoted membrane preparations were incubated with 0.16 nM [3H]spiperone (PerkinElmer) in the presence or absence of test compound in 96-well plates...More data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Test compounds were diluted serially in DMSO and subsequently diluted to 5% DMSO (v/w) in binding buffer (50 mM Tris, 5 mM MgCl2, 5 mM KCl, 1 mM CaCl...More data for this Ligand-Target Pair
Affinity DataEC50: 1.32nMAssay Description:Agonist activity at human D2L receptors was assayed by measuring cAMP levels in CHO-K1 cells expressing human D2L receptors (Eurofins DiscoverX, Frem...More data for this Ligand-Target Pair
Affinity DataEC50: 1.95nMAssay Description:Agonist activity at human D3 receptors was assayed by cAMP levels in HEK293 cells expressing recombinant human D3 receptors (BioXtal, Saint-Félix, Fr...More data for this Ligand-Target Pair
Affinity DataEC50: 1.95nMAssay Description:Agonist activity at human D3 receptors was assayed by cAMP levels in HEK293 cells expressing recombinant human D3 receptors (BioXtal, Saint-Félix, Fr...More data for this Ligand-Target Pair
Affinity DataKi: 1.95nMAssay Description:Test compounds were diluted serially in DMSO and subsequently diluted to 5% DMSO (v/w) in binding buffer (50 mM Tris, 5 mM MgCl2, 5 mM KCl, 1 mM CaCl...More data for this Ligand-Target Pair
Affinity DataKi: 1.95nMAssay Description:Test compounds were diluted serially in DMSO and subsequently diluted to 5% DMSO (v/w) in binding buffer (50 mM Tris, 5 mM MgCl2, 5 mM KCl, 1 mM CaCl...More data for this Ligand-Target Pair
Affinity DataEC50: 1.95nMAssay Description:PathHunter CHO-K1 cells expressing tagged human D2L receptors and tagged β-arrestin-2 (Eurofins DiscoverX, Fremont, CA, USA) were seeded into 96-well...More data for this Ligand-Target Pair
Affinity DataEC50: 2.82nMAssay Description:PathHunter CHO-K1 cells expressing tagged human D3 receptors and tagged β-arrestin-2 (Eurofins DiscoverX, Fremont, CA, USA) were seeded into 96-well ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.09nMAssay Description:PathHunter CHO-K1 cells expressing tagged human D3 receptors and tagged β-arrestin-2 (Eurofins DiscoverX, Fremont, CA, USA) were seeded into 96-well ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.55nMAssay Description:Agonist activity at human D3 receptors was assayed by cAMP levels in HEK293 cells expressing recombinant human D3 receptors (BioXtal, Saint-Félix, Fr...More data for this Ligand-Target Pair
Affinity DataEC50: 3.72nMAssay Description:Agonist activity at human D2L receptors was assayed by measuring cAMP levels in CHO-K1 cells expressing human D2L receptors (Eurofins DiscoverX, Frem...More data for this Ligand-Target Pair
Affinity DataEC50: 3.72nMAssay Description:Agonist activity at human D2L receptors was assayed by measuring cAMP levels in CHO-K1 cells expressing human D2L receptors (Eurofins DiscoverX, Frem...More data for this Ligand-Target Pair
Affinity DataEC50: 3.89nMAssay Description:PathHunter CHO-K1 cells expressing tagged human D3 receptors and tagged β-arrestin-2 (Eurofins DiscoverX, Fremont, CA, USA) were seeded into 96-well ...More data for this Ligand-Target Pair
Affinity DataKi: 15.5nMAssay Description:Receptor membranes were prepared from the CHO-K1 recombinant AequoScreen® cell line stably expressing the human 5-HT2A receptor (PerkinElmer, Waltham...More data for this Ligand-Target Pair
Affinity DataKi: 22.9nMAssay Description:Receptor membranes were prepared from the CHO-K1 recombinant AequoScreen® cell line stably expressing the human 5-HT2A receptor (PerkinElmer, Waltham...More data for this Ligand-Target Pair
Affinity DataKi: 29.5nMAssay Description:Receptor membranes were prepared from the CHO-K1 recombinant AequoScreen® cell line stably expressing the human 5-HT2A receptor (PerkinElmer, Waltham...More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:CHO-K1 cells expressing human recombinant 5-HT2A receptors and Gα16 (purchased from Euroscreen Fast, Brussels, BE) in culture were cryopreserved acco...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:CHO-K1 cells expressing human recombinant 5-HT2A receptors and Gα16 (purchased from Euroscreen Fast, Brussels, BE) in culture were cryopreserved acco...More data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:CHO-K1 cells expressing human recombinant 5-HT2A receptors and Gα16 (purchased from Euroscreen Fast, Brussels, BE) in culture were cryopreserved acco...More data for this Ligand-Target Pair