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Found
14
Enz. Inhib. hit(s) with all data for entry = 13317
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778039
(5-[2-fluoro-6-hydroxy- 4-[(4-hydroxy-5-methyl- pyr...)
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Affinity Data
Ki: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778048
(5-[4-[(4-chloro-6- hydroxy-5-isobutyl- pyrimidin-2...)
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Affinity Data
Ki: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778047
(5-[2-fluoro-6-hydroxy- 4-[(4-hydroxy-5,6,7,8- tetr...)
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Affinity Data
Ki: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778044
(5-[2-fluoro-6-hydroxy- 4-[(4-hydroxy-5- isobutyl-p...)
Copy SMILES
Affinity Data
Ki: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778042
(5-[2-fluoro-6-hydroxy- 4-[(4-hydroxy-6- methoxy-py...)
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Affinity Data
Ki: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778041
(5-[2-fluoro-6-hydroxy- 4-[(4- hydroxyquinazolin-2-...)
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Affinity Data
Ki: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778046
(5-[2-fluoro-6-hydroxy- 4-[(4-hydroxy-6-methyl- 5-p...)
Copy SMILES
Affinity Data
Ki: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778045
(5-[4-[(4,6-dihydroxy-5- isobutyl-pyrimidin-2- yl)a...)
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Affinity Data
Ki: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778043
(5-[2-fluoro-6-hydroxy- 4-[(4-hydroxy-6-methyl- pyr...)
Copy SMILES
Affinity Data
Ki: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778040
(5-[2-fluoro-6-hydroxy- 4-[(4-hydroxypyrimidin- 2-y...)
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Affinity Data
Ki: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778035
(5-[2-fluoro-6-hydroxy- 4-(1,4,5,6- tetrahydropyrim...)
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Affinity Data
Ki: 7.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM50649522
(CHEMBL5618189 | US20250313554, Compound 3)
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Affinity Data
Ki: 30nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778038
(5-[4-[(5- chloropyrimidin-2- yl)amino]-2-fluoro-6-...)
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Affinity Data
Ki: 75nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Ness Therapeutics
US Patent
Ligand
BDBM778037
(5-[2-fluoro-6-hydroxy- 4-[(4-methylpyrimidin- 2-yl...)
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Affinity Data
Ki: >1.70E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent
Copy reaction URL
BDBM778047
