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Found
52
Enz. Inhib. hit(s) with all data for entry = 13336
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781937
(US20250320234, Compound 43)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781936
(US20250320234, Compound 42)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM722813
(US20250059213, Compound 35 | US20250320234, Compou...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781930
(US20250320234, Compound 36)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781945
(US20250320234, Compound 56)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781944
(US20250320234, Compound 55)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781943
(US20250320234, Compound 54)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781941
(US20250320234, Compound 52)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781940
(US20250320234, Compound 51)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781938
(US20250320234, Compound 44)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781919
(US20250320234, Compound 25)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781918
(US20250320234, Compound 24)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781917
(US20250320234, Compound 23)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781915
(US20250320234, Compound 21)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781914
(US20250320234, Compound 20)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781929
(US20250320234, Compound 35)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781928
(US20250320234, Compound 34)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM722800
(US20250059213, Compound 13 | US20250320234, Compou...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781926
(US20250320234, Compound 32)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781925
(US20250320234, Compound 31)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781905
(US20250320234, Compound 11)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781904
(US20250320234, Compound 10)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781903
(US20250320234, Compound 9)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781901
(US20250320234, Compound 7)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781900
(US20250320234, Compound 6)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781899
(US20250320234, Compound 5)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM722826
(US20250059213, Compound 50 | US20250320234, Compou...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781908
(US20250320234, Compound 14)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM722809
(US20250059213, Compound 29 | US20250320234, Compou...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781906
(US20250320234, Compound 12)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781946
(US20250320234, Compound 57)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM722825
(US20250059213, Compound 48 | US20250320234, Compou...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781848
(US20250320234, Compound 1)
Copy SMILES
Affinity Data
IC50: 50nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781921
(US20250320234, Compound 27)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781935
(US20250320234, Compound 41)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781902
(US20250320234, Compound 8)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781932
(US20250320234, Compound 38)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781912
(US20250320234, Compound 18)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM722815
(US20250059213, Compound 38 | US20250320234, Compou...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781911
(US20250320234, Compound 17)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781910
(US20250320234, Compound 16)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781909
(US20250320234, Compound 15)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781924
(US20250320234, Compound 30)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781939
(US20250320234, Compound 45)
Copy SMILES
Affinity Data
IC50: 275nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781920
(US20250320234, Compound 26)
Copy SMILES
Affinity Data
IC50: 2.75E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781934
(US20250320234, Compound 40)
Copy SMILES
Affinity Data
IC50: 2.75E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781933
(US20250320234, Compound 39)
Copy SMILES
Affinity Data
IC50: 2.75E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781913
(US20250320234, Compound 19)
Copy SMILES
Affinity Data
IC50: 2.75E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781942
(US20250320234, Compound 53)
Copy SMILES
Affinity Data
IC50: 2.75E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
Target
Lon protease homolog, mitochondrial
(Human)
Pretzel Therapeutics
US Patent
Ligand
BDBM781923
(US20250320234, Compound 29)
Copy SMILES
Affinity Data
IC50: 2.75E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent
Copy reaction URL
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