Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 5861
TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM1774(US8476284, 13 | US10894048, Ref. Ex Comp. 1)
Affinity DataIC50: 0.5nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
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Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97673(US8497277, 6 | US8476284, 41 | US20240358707, Comp...)
Affinity DataIC50: 0.520nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97677(US8497277, 7 | US8476284, 7 | US9133201, 7 | US202...)
Affinity DataIC50: 0.580nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
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Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97672(US8476284, 40 | US9133201, 10 | US9181263, 9 | US9...)
Affinity DataIC50: 0.580nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM1773(US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...)
Affinity DataIC50: 0.720nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97674(US8497277, 8 | US8476284, 42 | US9133201, 8 | US20...)
Affinity DataIC50: 0.720nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97669(US8497277, 14 | US8476284, 37 | US20240358707, Com...)
Affinity DataIC50: 1.40nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97671(US8476284, 39 | US9133201, 11 | US20240358707, Com...)
Affinity DataIC50: 1.60nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97670(US8476284, 38 | US9133201, 12 | US20240358707, Com...)
Affinity DataIC50: 1.90nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97675(BDBM698786 | US8497277, 15 | US9181263, 2 | US9278...)
Affinity DataIC50: 2.5nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97678(US8497277, 10 | US8497277, 9 | US8476284, 9 | US91...)
Affinity DataIC50: 3.60nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Pharmacyclics

US Patent
LigandPNGBDBM97676(US8497277, 5 | US8476284, 5 | US9133201, 5 | US202...)
Affinity DataIC50: 20nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase Lyn(Human)
Pharmacyclics

US Patent
LigandPNGBDBM1773(US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...)
Affinity DataKi:  14nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
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TargetTyrosine-protein kinase Lck(Human)
Pharmacyclics

US Patent
LigandPNGBDBM1773(US8497277, 4 | US8497277, 13 | US8476284, 4 | US91...)
Affinity DataKi:  97nMpH: 7.4Assay Description:Measurements were performed in a reaction volume of 50 μL using 96-well assay plates. Kinase enzyme, inhibitor, ATP (at the Km for the kinase), an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2013
Entry Details
Go to US Patent