Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 6031
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50222709(CHEMBL244488 | 3,4-difluoro-2-(2-fluoro-4-iodophen...)
Affinity DataIC50: 2nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104963(CHEMBL507361 | US8575391, Q | US11147816, PD032590...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104959(US8575391, G-2)
Affinity DataIC50: 7.20nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104951(US8575391, F-2)
Affinity DataIC50: 8.60nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50338038(US8575391, 334 | 3,4-difluoro-2-[(2-fluoro-4-iodop...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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PDB3D3D Structure (crystal)
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104949(US8575391, C-31)
Affinity DataIC50: 12nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104939(US8575391, B-9)
Affinity DataIC50: 15nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104941(US8575391, C-1)
Affinity DataIC50: 19nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104945(US8575391, C-10)
Affinity DataIC50: 19nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104936(US8575391, B-1)
Affinity DataIC50: 21nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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PDB3D3D Structure (crystal)
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104938(US8575391, B-6)
Affinity DataIC50: 23nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104946(US8575391, C-13)
Affinity DataIC50: 28nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104955(US8575391, F-6)
Affinity DataIC50: 28nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104952(US8575391, F-3)
Affinity DataIC50: 29nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104940(US8575391, B-12)
Affinity DataIC50: 31nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104937(US8575391, B-2)
Affinity DataIC50: 32nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104944(US8575391, C-8)
Affinity DataIC50: 32nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104950(US8575391, F-1)
Affinity DataIC50: 35nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104953(US8575391, F-4)
Affinity DataIC50: 35nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104960(US8575391, G-3)
Affinity DataIC50: 37nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104962(US8575391, G-5)
Affinity DataIC50: 40nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104954(US8575391, F-5)
Affinity DataIC50: 43nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104956(US8575391, F-7)
Affinity DataIC50: 48nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104942(US8575391, C-6)
Affinity DataIC50: 49nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104961(US8575391, G-4)
Affinity DataIC50: 56nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104957(US8575391, F-8)
Affinity DataIC50: 65nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104948(US8575391, C-28)
Affinity DataIC50: 68nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104947(US8575391, C-24)
Affinity DataIC50: 68nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104958(US8575391, F-9)
Affinity DataIC50: 70nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50132260(CHEMBL105442 | US8575391, 341 | CI-1040 | 2-(2-chl...)
Affinity DataIC50: 130nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM104943(US8575391, C-7)
Affinity DataIC50: 140nMAssay Description:Inhibition assay using MEK kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent