Compile Data Set for Download or QSAR
Report error Found 95 Enz. Inhib. hit(s) with all data for entry = 6385
TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125902(US8765727, 5)
Affinity DataIC50: 1.90nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
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Date in BDB:
11/24/2014
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125902(US8765727, 5)
Affinity DataIC50: 2.40nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
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Date in BDB:
11/24/2014
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125902(US8765727, 5)
Affinity DataIC50: 4.20nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125913(US8765727, 16)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
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Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125904(US8765727, 7)
Affinity DataIC50: 6.40nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
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Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125904(US8765727, 7)
Affinity DataIC50: 8.30nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125899(US8765727, 2)
Affinity DataIC50: 9.20nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125899(US8765727, 2)
Affinity DataIC50: 10nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125899(US8765727, 2)
Affinity DataIC50: 13nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125913(US8765727, 16)
Affinity DataIC50: 15nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125913(US8765727, 16)
Affinity DataIC50: 15nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125904(US8765727, 7)
Affinity DataIC50: 16nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125898(US8765727, 1)
Affinity DataIC50: 17nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125901(US8765727, 4)
Affinity DataIC50: 21nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125906(US8765727, 9)
Affinity DataIC50: 23nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandPNGBDBM125902(US8765727, 5)
Affinity DataIC50: 25nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125910(US8765727, 13)
Affinity DataIC50: 25nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125906(US8765727, 9)
Affinity DataIC50: 28nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125912(US8765727, 15)
Affinity DataIC50: 31nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125910(US8765727, 13)
Affinity DataIC50: 32nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandPNGBDBM125899(US8765727, 2)
Affinity DataIC50: 35nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125912(US8765727, 15)
Affinity DataIC50: 41nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandPNGBDBM125904(US8765727, 7)
Affinity DataIC50: 43nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125898(US8765727, 1)
Affinity DataIC50: 49nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125898(US8765727, 1)
Affinity DataIC50: 51nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandPNGBDBM125906(US8765727, 9)
Affinity DataIC50: 53nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125906(US8765727, 9)
Affinity DataIC50: 55nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125911(US8765727, 14)
Affinity DataIC50: 57nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125910(US8765727, 13)
Affinity DataIC50: 62nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125912(US8765727, 15)
Affinity DataIC50: 81nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125911(US8765727, 14)
Affinity DataIC50: 91nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125901(US8765727, 4)
Affinity DataIC50: 96nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125911(US8765727, 14)
Affinity DataIC50: 100nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125914(US8765727, 17)
Affinity DataIC50: 102nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125901(US8765727, 4)
Affinity DataIC50: 104nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandPNGBDBM125910(US8765727, 13)
Affinity DataIC50: 106nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125914(US8765727, 17)
Affinity DataIC50: 114nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125907(US8765727, 10)
Affinity DataIC50: 117nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Incyte

US Patent
LigandPNGBDBM125909(US8765727, 12)
Affinity DataIC50: 120nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125907(US8765727, 10)
Affinity DataIC50: 122nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125903(US8765727, 6)
Affinity DataIC50: 140nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandPNGBDBM125913(US8765727, 16)
Affinity DataIC50: 149nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125907(US8765727, 10)
Affinity DataIC50: 180nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandPNGBDBM125907(US8765727, 10)
Affinity DataIC50: 237nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetALK tyrosine kinase receptor(Human)
Incyte

US Patent
LigandPNGBDBM125913(US8765727, 16)
Affinity DataIC50: 280nMpH: 7.8Assay Description:HTRF kinase assay: 40 μL reactions were run in black 384 well polystyrene plates in assay buffer (50 mM Tris, pH 7.8, 100 mM NaCI, 0.1 mg/mL BSA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125905(US8765727, 8)
Affinity DataIC50: 300nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Incyte

US Patent
LigandPNGBDBM125911(US8765727, 14)
Affinity DataIC50: 300nMAssay Description:TYK2 assays described by James E. Thompson et. al, Photochemical preparation of a pyridone containing tetracycle: A JAK protein kinase inhibitor, Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125900(US8765727, 3)
Affinity DataIC50: 300nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandPNGBDBM125909(US8765727, 12)
Affinity DataIC50: 300nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Incyte

US Patent
LigandPNGBDBM125909(US8765727, 12)
Affinity DataIC50: 315nMpH: 7.8 T: 2°CAssay Description:One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
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