Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 6547
TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138357(US8877795, 6 | US10278929, Compound 6 | US11337935...)
Affinity DataIC50: 277nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM85507(NSC_4488 | CAS_4394-00-7 | Niflumic acid (Hit 16) ...)
Affinity DataIC50: 289nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138358(US8877795, 7 | US10278929, Compound 7 | US11337935...)
Affinity DataIC50: 296nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50308343((Z)-5-(3,5-dibromo-4-methoxybenzylidene)thiazolidi...)
Affinity DataIC50: 301nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138359(US8877795, 9 | US10278929, Compound 9 | US11337935...)
Affinity DataIC50: 329nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138360(US8877795, 10 | US10278929, Compound 10 | US113379...)
Affinity DataIC50: 433nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138361(US8877795, Meclofenamic Acid)
Affinity DataIC50: 504nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138362(US8877795, 11)
Affinity DataIC50: 586nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 653nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50017846(CHEMBL168276 | 3,5-DINITROCATECHOL | 3,5-Dinitro-b...)
Affinity DataIC50: 741nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138363(US8877795, Ro 41-0960 | US10278929, Compound Ro-41...)
Affinity DataIC50: 755nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138364(US8877795, 12 | US10278929, Compound 12 | US113379...)
Affinity DataIC50: 815nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50334179(5-(naphthalen-1-ylmethylene)thiazolidine-2,4-dione...)
Affinity DataIC50: 842nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138365(US8877795, 14 | US10278929, Compound 14 | US113379...)
Affinity DataIC50: 1.15E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138366(US8877795, 15 | US10278929, Compound 15 | US113379...)
Affinity DataIC50: 1.31E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138367(US8877795, 16 | US10278929, Compound 16 | US113379...)
Affinity DataIC50: 2.59E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138368(US8877795, 17 | US10278929, Compound 17 | US113379...)
Affinity DataIC50: 2.66E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138369(US8877795, 18 | US10278929, Compound 18 | US113379...)
Affinity DataIC50: 3.35E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138370(US8877795, 19 | US10278929, Compound 19 | US113379...)
Affinity DataIC50: 3.71E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138371(US8877795, Diclofenac | US10278929, Diclofenac)
Affinity DataIC50: 3.74E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138372(US8877795, 20 | US10278929, Compound 20 | US113379...)
Affinity DataIC50: 3.93E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138373(US8877795, 21 | US10278929, Compound 21 | US113379...)
Affinity DataIC50: 4.22E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM50355116(CHEMBL493923 | US10278929, Compound 22 | US1133793...)
Affinity DataIC50: 4.79E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138374(US8877795, 23 | US10278929, Compound 23 | US113379...)
Affinity DataIC50: 4.88E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138375(US8877795, 24 | US10278929, Compound 24 | US113379...)
Affinity DataIC50: 4.93E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138376(US8877795, 25 | US10278929, Compound 25 | US113379...)
Affinity DataIC50: 5.41E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138377(US8877795, 26 | US10278929, Compound 26 | US113379...)
Affinity DataIC50: 5.60E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138378(US8877795, 27 | US10278929, Compound 27 | US113379...)
Affinity DataIC50: 5.80E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138379(US8877795, 28 | US10278929, Compound 28 | US113379...)
Affinity DataIC50: 8.69E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138380(US8877795, 29 | US10278929, Compound 29 | US113379...)
Affinity DataIC50: 9.76E+3nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138381(US8877795, 30 | US10278929, Compound 30 | US113379...)
Affinity DataIC50: 1.00E+4nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138382(US8877795, 31 | US10278929, Compound 31 | US113379...)
Affinity DataIC50: 1.06E+4nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetTransthyretin(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM138383(US8877795, 32 | US10278929, Compound 32 | US113379...)
Affinity DataIC50: 1.10E+4nMAssay Description:The FP assay was then adapted for HTS and used to screen ~120,000 small molecule library for compounds that displaced probe 5 from the T4 binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent