Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 6590
TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM140273(US8907086, Example 5)
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM140267(US8907086, Example 1)
Affinity DataIC50: 5.70nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM140271(US8907086, Example 7)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM47061(US8907086, Example 2)
Affinity DataIC50: 34nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM140272(US8907086, Example 8)
Affinity DataIC50: 104nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM140268(US8907086, Example 6)
Affinity DataIC50: 106nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM140269(US8907086, Example 2 | US8907086, Example 3)
Affinity DataIC50: 1.34E+3nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM140270(US8907086, Example 4)
Affinity DataIC50: 1.59E+3nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent