Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 6624
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142014(US8927539, 1)
Affinity DataIC50: 3.70nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142010(US8927539, 3)
Affinity DataIC50: 4.90nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142013(US8927539, 8)
Affinity DataIC50: 5.30nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142009(US8927539, 2)
Affinity DataIC50: 5.60nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142015(US8927539, 4)
Affinity DataIC50: 23nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142017(US8927539, 9)
Affinity DataIC50: 37nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142018(US8927539, 10)
Affinity DataIC50: 38nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142011(US8927539, 5)
Affinity DataIC50: 39nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142016(US8927539, 6)
Affinity DataIC50: 74nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142012(US8927539, 7)
Affinity DataIC50: 100nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
Go to US Patent