Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 6873
TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM155343(US9006249, Example 49-2 | US9603819, Example 49-2)
Affinity DataIC50: 0.0300nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153121(US8993631, 29-2 | US9006249, Example 49-1)
Affinity DataIC50: 0.0400nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM155344(US9006249, Example 49-3 | US9603819, Example 49-3)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153108(US8993631, 16-5 | US9006249, Example 3-32 | US9603...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153109(US8993631, 16-8 | US9006249, Example 3-60)
Affinity DataIC50: 7.30nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM155342(US9006249, Example 13-1)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153116(US8993631, 19 | US9006249, Example 7-1 | US9603819...)
Affinity DataIC50: 93nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153117(US8993631, 20 | US9006249, Example 9-1 | US9603819...)
Affinity DataIC50: 142nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153107(US8993631, 16-3 | US9006249, Example 3-6 | US96038...)
Affinity DataIC50: 250nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153113(US8993631, 15-1 | US9006249, Example 2-1 | US96038...)
Affinity DataIC50: 267nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153112(US8993631, 14-1 | US9006249, Example 1-1 | US96038...)
Affinity DataIC50: 283nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153114(US8993631, 17 | US9006249, Example 5-1 | US9603819...)
Affinity DataIC50: 350nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
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TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153115(US8993631, 18-1 | US9006249, Example 6-1 | US96038...)
Affinity DataIC50: 450nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
Go to US Patent