Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 7374
TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM191990(US9718787, 124 | US9187430, 124)
Affinity DataIC50: 6nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM191991(US9718787, 126 | US9187430, 126)
Affinity DataIC50: 7nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM191984(US9718787, 61 | US9187430, 61)
Affinity DataIC50: 8nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM191985(US9718787, 85 | US9187430, 85)
Affinity DataIC50: 9nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 12nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM191989(US9718787, 107 | US9187430, 107)
Affinity DataIC50: 13nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM191986(US9718787, 88 | US9187430, 88)
Affinity DataIC50: 15nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM191987(US9718787, 99 | US9187430, 99)
Affinity DataIC50: 17nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Chengdu Di'Ao Pharmaceutical Group

US Patent
LigandPNGBDBM191988(US9718787, 100 | US9187430, 100)
Affinity DataIC50: 30nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent