Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 8049
TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM50393095(CHEMBL2152910 | US9346827, 14)
Affinity DataIC50: 0.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM50393096(CHEMBL2152911 | US9346827, 15)
Affinity DataIC50: 0.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231557(US9346827, 2)
Affinity DataIC50: 1nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231561(US9346827, 4)
Affinity DataIC50: 1nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231564(US9346827, 18)
Affinity DataIC50: 2nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231565(US9346827, 19)
Affinity DataIC50: 3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231558(US9346827, 17 | US9346827, 13)
Affinity DataIC50: 139nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231562(US9346827, 16)
Affinity DataIC50: 285nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231558(US9346827, 17 | US9346827, 13)
Affinity DataIC50: 369nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231559(US9346827, 3B)
Affinity DataIC50: 3.83E+3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
6/5/2017
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM231560(US9346827, 3A)
Affinity DataIC50: 9.23E+3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent