Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 8219
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Denver and Regis University

US Patent
LigandPNGBDBM382(8-oxidanylquinoline-2-carboxylic acid | ST086494 |...)
Affinity DataIC50: 1.70E+4nM Kd:  6.94E+3nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Denver and Regis University

US Patent
LigandPNGBDBM382(8-oxidanylquinoline-2-carboxylic acid | ST086494 |...)
Affinity DataIC50: 1.40E+4nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Denver and Regis University

US Patent
LigandPNGBDBM32144(cid_11359 | AS-232 | quinolin-8-amine | 8-quinolin...)
Affinity DataIC50: 7.90E+4nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Denver and Regis University

US Patent
LigandPNGBDBM32203(cid_1923 | CHEMBL310555 | 8-quinolinol | quinolin-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Denver and Regis University

US Patent
LigandPNGBDBM237137(US9394254, 34)
Affinity DataIC50: 5.70E+5nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent