Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8333
TargetGenome polyprotein [1027-1207,D168A](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50: 25nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
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TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50: 53nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
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TargetGenome polyprotein [1027-1207,D168A](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50: 98nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241943(US9422333, I-23)
Affinity DataIC50: 111nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
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TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50: 232nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 290nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,D168A](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 312nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,D168A](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50: 321nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
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TargetGenome polyprotein [1027-1207,A156S](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241943(US9422333, I-23)
Affinity DataIC50: 412nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50: 456nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241943(US9422333, I-23)
Affinity DataIC50: 463nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,D168A](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241943(US9422333, I-23)
Affinity DataIC50: 508nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,R155K](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 928nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,A156T](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241943(US9422333, I-23)
Affinity DataIC50: 985nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,R155K](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50: 1.05E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,C159S](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 1.09E+3nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,D168A](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50: 1.15E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 1.33E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50: 1.74E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,C159S](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50: 2.07E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,D168A](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 2.55E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,A156S](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,C159S](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,R155K](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241942(US9422333, I-11)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,R155K](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,A156S](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,A156S](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [1027-1207,C159S](Hepacivirus C)
Celgene Avilomics Research

US Patent
LigandPNGBDBM241940(US9422333, I-1)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent