Compile Data Set for Download or QSAR
Report error Found 169 Enz. Inhib. hit(s) with all data for entry = 858
TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294419(US9586959, Compound 98)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294378(US9586959, Compound 31)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294427(US9586959, Compound disclosed in WO 2010030785, Ex...)
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294418(US9586959, Compound 96)
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 24 | US9586959, Compound 68 | ...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294386(US9586959, Compound 49)
Affinity DataIC50: 34nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50: 35nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 24 | US9586959, Compound 68 | ...)
Affinity DataIC50: 36nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294361(US9586959, Compound 4)
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294414(US9586959, Compound 92)
Affinity DataIC50: 42nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50: 44nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294377(US9586959, Compound 29)
Affinity DataIC50: 49nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294368(US9586959, Compound 18)
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294408(US9586959, Compound 74)
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294416(US9586959, Compound 94)
Affinity DataIC50: 62nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294409(US9586959, Compound 75)
Affinity DataIC50: 64nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294366(US9586959, Compound 16)
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294385(US9586959, Compound 48)
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294415(US9586959, Compound 93)
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294364(US9586959, Compound 12)
Affinity DataIC50: 67nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294382(US9586959, Compound 43)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294379(US9586959, Compound 32)
Affinity DataIC50: 73nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294374(US9586959, Compound 25)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294381(US9586959, Compound 39)
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 24 | US9586959, Compound 68 | ...)
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294362(US9586959, Compound 7)
Affinity DataIC50: 133nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294372(US9586959, Compound 23)
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294383(US9586959, Compound 46)
Affinity DataIC50: 154nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294423(US9586959, Compound 110)
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294380(US9586959, Compound 35)
Affinity DataIC50: 170nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294367(US9586959, Compound 17)
Affinity DataIC50: 177nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294387(US9586959, Compound 50)
Affinity DataIC50: 190nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294391(US9586959, Compound 54)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294393(US9586959, Compound 58)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294426(US9586959, Compound 117)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294375(US9586959, Compound 26)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294389(US9586959, Compound 52)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294420(US9586959, Compound 100)
Affinity DataIC50: 231nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294365(US9586959, Compound 13)
Affinity DataIC50: 238nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294398(US9586959, Compound 64)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294424(US9586959, Compound 111)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294425(US9586959, Compound 116)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294392(US9586959, Compound 55)
Affinity DataIC50: 260nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294412(US9586959, Compound 88)
Affinity DataIC50: 260nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294371(US9586959, Compound 21)
Affinity DataIC50: 270nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294390(US9586959, Compound 53)
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294401(US9586959, Compound 66)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294405(US9586959, Compound 67)
Affinity DataIC50: 314nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294413(US9586959, Compound 89)
Affinity DataIC50: 360nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294370(US9586959, Compound 20)
Affinity DataIC50: 380nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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