Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 1192
TargetD(2) dopamine receptor(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataKi:  0.300nM IC50: 0.980nMAssay Description:Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Compound: Haloperidol Incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetD(2) dopamine receptor(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataKi:  0.610nM IC50: 1.96nMAssay Description:Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Compound: Haloperidol Incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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Target5-hydroxytryptamine receptor 1A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataKi:  0.650nM IC50: 0.970nMAssay Description:Receptor Source: Human recombinant expressed in HEK-293 cells Radioligand: [3H]-8-OH-DPAT (221 Ci/mmol) Control Compound: 8-OH-DPAT Incubati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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Target5-hydroxytryptamine receptor 1A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataKi:  1.5nM IC50: 2.25nMAssay Description:Receptor Source: Human recombinant expressed in HEK-293 cells Radioligand: [3H]-8-OH-DPAT (221 Ci/mmol) Control Compound: 8-OH-DPAT Incubati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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Target5-hydroxytryptamine receptor 2A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataKi:  58.5nM IC50: 130nMAssay Description:Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketanserin Incubation Conditions: The reactions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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Target5-hydroxytryptamine receptor 2A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataKi:  118nM IC50: 262nMAssay Description:Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketanserin Incubation Conditions: The reactions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent