Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 1318
TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293900(US10106535, Example 26 | (S)-3-(5-Chloro-6- methyl...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293916(US10106535, Example 42 | (S)-1-(3,4-Difluoro-2- me...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293899(US10106535, Example 25 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293880(US10106535, Example 6 | (S)-1-(3-Fluoro-2- methylp...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293914(US10106535, Example 40 | (S)-3-(Benzo[d]thiazol-5-...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293912(US10106535, Example 38 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293911(US10106535, Example 37 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293895(US10106535, Example 21 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293886(US10106535, Example 12 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 10nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293876(US10106535, Example 2 | (S)-1-(3-Fluoro-2- methylp...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293898(US10106535, Example 24 | (S)-3-(2- Cyclopropylpyri...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293901(US10106535, Example 27 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293902(US10106535, Example 28 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293892(US10106535, Example 18 | (S)-3-(1-(Difluoromethyl)...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293890(US10106535, Example 16 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293910(US10106535, Example 36 | (S)-3-(5-Chloro-2- methyl...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293885(US10106535, Example 11 | (S)-3-(5-Chloropyridin-3-...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293915(US10106535, Example 41 | (S)-3-(Benzo[b]thiophen- ...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293878(US10106535, Example 4 | (S)-1-(3-Fluoro-2- methylp...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293891(US10106535, Example 17 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 30nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293888(US10106535, Example 14 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 30nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293903(US10106535, Example 29 | (S)-3-(Benzo[d]isothiazol...)
Affinity DataIC50: 30nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293896(US10106535, Example 22 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 30nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293913(US10106535, Example 39 | (S)-3-(1-(Difluoromethyl)...)
Affinity DataIC50: 30nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293906(US10106535, Example 32 | (S)-3-Cyclopropyl-1-(3- f...)
Affinity DataIC50: 40nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293897(US10106535, Example 23 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 40nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM316849(US9617259, 10 | (S)-1-(3-Fluoro-2- methylphenyl)-N...)
Affinity DataIC50: 40nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293893(US10106535, Example 19 | (S)-3-(2-Cyclopropyl-5- f...)
Affinity DataIC50: 40nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293887(US10106535, Example 13 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 40nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293889(US10106535, Example 15 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 40nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293894(US10106535, Example 20 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 70nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293907(US10106535, Example 33 | (S)-N-Hydroxy-1,3- diphen...)
Affinity DataIC50: 190nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293877(US10106535, Example 3 | (R)-1-(3-Fluoro-2- methylp...)
Affinity DataIC50: 230nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293909(US10106535, Example 35 | (S)-3-(5-Fluoropyridin-3-...)
Affinity DataIC50: 340nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293918(US10106535, Example 44 | 3'-Fluoro-4-(5- fluoropyr...)
Affinity DataIC50: 490nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293919(US10106535, Example 45 | (S)-1-(3-Fluoro-2- methyl...)
Affinity DataIC50: 550nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293879(US10106535, Example 5 | (R)-1-(3-Fluoro-2- methylp...)
Affinity DataIC50: 670nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293882(US10106535, Example 8 | (S)-1-(3-Fluoro-2- methylp...)
Affinity DataIC50: 2.40E+3nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293917(US10106535, Example 43 | 4-(5-Fluoropyridin-3-yl)-...)
Affinity DataIC50: 3.60E+3nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293875(US10106535, Example 1 | (R)-1-(3-Fluoro-2- methylp...)
Affinity DataIC50: 7.60E+3nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293905(US10106535, Example 31 | 1-(2-Fluorophenyl)-N- hyd...)
Affinity DataIC50: 8.30E+3nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM316869(US9617259, 30 | N-Hydroxy-1- phenylcyclopent-3- en...)
Affinity DataIC50: 1.23E+4nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM316848(US9617259, 9 | (R)-1-(3-Fluoro-2- methylphenyl)-N-...)
Affinity DataIC50: 2.68E+4nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293908(US10106535, Example 34 | (R)-N-Hydroxy-1,3- diphen...)
Affinity DataIC50: 3.10E+4nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293881(US10106535, Example 7 | (R)-1-(3-Fluoro-2- methylp...)
Affinity DataIC50: 5.00E+4nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
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