Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 1330
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317225(US9617281, Compound 6 | 6-(Azepan-1- ylmethyl)-2- ...)
Affinity DataKi:  16nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317227(US9617281, Compound 9 | 6-((2-(Azepan-1- ylethoxy)...)
Affinity DataKi:  40nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317226(US9617281, Compound 7 | 6-((4- Methylpiperazin-1- ...)
Affinity DataKi:  56nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317230(US9617281, Compound 12 | 2-(Azepan-1- ylmethyl)-6-...)
Affinity DataKi:  100nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317218(US9617281, Compound 4)
Affinity DataKi:  168nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317228(US9617281, Compound 10 | 2-Phenyl-6-((2- (pyrrolid...)
Affinity DataKi:  190nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317231(US9617281, Compound 13 | 2-(4-Fluorophenyl)- 6-((4...)
Affinity DataKi:  210nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317229(US9617281, Compound 11 | 6-((4- Methylpiperazin-1-...)
Affinity DataKi:  260nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent