Compile Data Set for Download or QSAR
Report error Found 248 Enz. Inhib. hit(s) with all data for entry = 1475
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325610(US9636336, Example 105c)
Affinity DataKi:  0.230nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325606(US9636336, Example 87c)
Affinity DataKi:  0.300nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325610(US9636336, Example 105c)
Affinity DataIC50: 0.450nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325606(US9636336, Example 87c)
Affinity DataIC50: 0.5nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325608(US9636336, Example 78c)
Affinity DataKi:  0.540nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325607(US9636336, Example 78 | US9636336, Example 77 | [(...)
Affinity DataKi:  0.590nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | [(...)
Affinity DataKi:  0.700nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325609(US9636336, Example 105 | US9636336, Example 106 | ...)
Affinity DataKi:  0.850nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325646(US9636336, Example 37 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325646(US9636336, Example 37 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325647(US9636336, Example 38 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325647(US9636336, Example 38 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325648([(1S)-2-(3,5-dichloro-1-oxido-pyridin-1-ium-4-yl)-...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325642(US9636336, Example 33 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325642(US9636336, Example 33 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325645(US9636336, Example 36 | US9636336, Example 108 | U...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325609(US9636336, Example 105 | US9636336, Example 106 | ...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325645(US9636336, Example 36 | US9636336, Example 108 | U...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325645(US9636336, Example 36 | US9636336, Example 108 | U...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325714([(1S)-2-(3,5-dichloro-1-oxido-pyridin-1-ium-4-yl)-...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325653(US9636336, Example 47 | US9636336, Example 48 | [1...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325716(US9636336, Example 120 | US9636336, Example 125 | ...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325624([(1S)-2-(3,5-dichloro-1-oxido-pyridin-1-ium-4-yl)-...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325650(US9636336, Example 44 | US9636336, Example 45 | [(...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325713([(1S)-2-(3,5-dichloro-1-oxido-pyridin-1-ium-4-yl)-...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325614(US9636336, Example 4 | US9636336, Example 55 | US9...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325614(US9636336, Example 4 | US9636336, Example 55 | US9...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325711(US9636336, Example 115 | US9636336, Example 127 | ...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325711(US9636336, Example 115 | US9636336, Example 127 | ...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325615(US9636336, Example 5 | US9636336, Example 57 | US9...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325712(US9636336, Example 116 | US9636336, Example 129 | ...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325664(US9636336, Example 59 | [1-[3-(cyclopropylmethoxy)...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325715(US9636336, Example 119 | [(1S)-2-(3,5-dichloro-1-o...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325613(US9636336, Example 53 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325614(US9636336, Example 4 | US9636336, Example 55 | US9...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325716(US9636336, Example 120 | US9636336, Example 125 | ...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325622(US9636336, Example 67 | US9636336, Example 68 | [2...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325622(US9636336, Example 67 | US9636336, Example 68 | [2...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325664(US9636336, Example 59 | [1-[3-(cyclopropylmethoxy)...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325664(US9636336, Example 59 | [1-[3-(cyclopropylmethoxy)...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325619(US9636336, Example 9 | US9636336, Example 62 | [(1...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325620(US9636336, Example 10 | US9636336, Example 64 | US...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325620(US9636336, Example 10 | US9636336, Example 64 | US...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325614(US9636336, Example 4 | US9636336, Example 55 | US9...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325626(US9636336, Example 16 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325615(US9636336, Example 5 | US9636336, Example 57 | US9...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325623(US9636336, Example 69 | [(1S)-1-[3-(cyclopropylmet...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM325625(US9636336, Example 15 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325621(US9636336, Example 11 | [(1S)-2-(3,5-dichloro-1-ox...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM325622(US9636336, Example 67 | US9636336, Example 68 | [2...)
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

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