Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 89
TargetCytochrome P450 3A4(Human)
Brickell Biotech

US Patent
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 20nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
Brickell Biotech

US Patent
LigandPNGBDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 20nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetCytochrome P450 2D6(Human)
Brickell Biotech

US Patent
LigandPNGBDBM190405(US9180183, Quinidine)
Affinity DataIC50: 40nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Brickell Biotech

US Patent
LigandPNGBDBM50090677(CHEMBL1109 | 4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-...)
Affinity DataIC50: 210nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Brickell Biotech

US Patent
LigandPNGBDBM50236897(furafylline | 3-(furan-2-ylmethyl)-1,8-dimethyl-1H...)
Affinity DataIC50: 2.20E+3nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Brickell Biotech

US Patent
LigandPNGBDBM50267074(Phenobarbital | N-3-benzyl-phenobarbital | CHEMBL4...)
Affinity DataIC50: 8.70E+3nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Brickell Biotech

US Patent
LigandPNGBDBM164620(US9688624, Compound 2)
Affinity DataIC50: 2.60E+4nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Brickell Biotech

US Patent
LigandPNGBDBM164620(US9688624, Compound 2)
Affinity DataIC50: 5.00E+4nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Brickell Biotech

US Patent
LigandPNGBDBM164620(US9688624, Compound 2)
Affinity DataIC50: 5.00E+4nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Brickell Biotech

US Patent
LigandPNGBDBM164620(US9688624, Compound 2)
Affinity DataIC50: 5.00E+4nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Brickell Biotech

US Patent
LigandPNGBDBM164620(US9688624, Compound 2)
Affinity DataIC50: 5.00E+4nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Brickell Biotech

US Patent
LigandPNGBDBM164620(US9688624, Compound 2)
Affinity DataIC50: 5.00E+4nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent