Compile Data Set for Download or QSAR
Report error Found 182 Enz. Inhib. hit(s) with all data for entry = 415
TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267245(3-chloro-5-((6-oxo-1-((6-oxo-5-phenyl-1,6-dihydrop...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267252(3-chloro-5-((1-((5- (3,4-difluorophenyl)- 6-oxo-1,...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267287(3-chloro-5-((1-((5- (2,3- dihydrobenzofuran-5- yl)...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267334(3-chloro-5-((6-oxo-1-((3-oxo-6-phenyl-2,3-dihydrop...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267344(3-chloro-5-((1-((6- (2,3- difluorophenyl)-3- oxo-2...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267389(2-fluoro-3-((1-((5-(4-fluorophenyl)-6-oxo-1,6-dihy...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267390(3-chloro-5-((1-((5-(4- fluorophenyl)-6-oxo- 1,6-di...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267395(3-((4-(1,1-difluoroethyl)-1-((5-(4-fluorophenyl)-6...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267399(3-chloro-5-((4-(1,1- difluoroethyl)-1-((6- (difluo...)
Affinity DataIC50: 3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267253(3-chloro-5-((1-((5-(4- (difluoromethoxy) phenyl)-6...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267259(3-chloro-5-((1-((5-(3- chlorophenyl)-6-oxo- 1,6-di...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267267(3-chloro-5-((1-((5-(2- fluoro-3- methoxyphenyl)-6-...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267275(3-chloro-5-((1-((5-(3- fluoro-4- methoxyphenyl)-6-...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267281(3-chloro-5-((1-((5-(3- fluoro-4- methylphenyl)-6-o...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267300(3-chloro-5-((1-((5-(4-fluorophenyl)-6-oxo-1,6-dihy...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267350(3-chloro-5-((6-oxo- 1-((3-oxo-6-(1H- pyrrolo[2,3- ...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267352(3-chloro-5-((1-((6-(difluoromethyl)-3-oxo-2,3-dihy...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267393(3-chloro-5-((1-((5-(4-fluorophenyl)-6-oxo-1,6-dihy...)
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267241(2,5-dichloro-3-((6-oxo-1-((6-oxo-1,6-dihydropyrida...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267249(3-chloro-5-((1-((5(3- fluorophenyl)-6-oxo- 1,6-dih...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267251(3-chloro-5-((1-((5-(4- chlorophenyl)-6-oxo- 1,6-di...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267254(3-chloro-5-((6-oxo-1- ((6-oxo-5-(p-tolyl)- 1,6-dih...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267260(3-chloro-5-((1-((5-(4- fluoro-3- methylphenyl)-6-o...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267269(3-chloro-5-((1-((5-(4- chloro-3- fluorophenyl)-6-o...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267288(3-chloro-5-((6-oxo-1- ((6-oxo-5-(1H- pyrazol-5-yl)...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267294(3-chloro-5-((6-oxo-1- ((6-oxo-5-(1H- pyrazol-4-yl)...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267336(3-chloro-5-((1-((6- (4-fluorophenyl)-3- oxo-2,3- d...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267345(3-chloro-5-((1-((6- (3,4- difluorophenyl)-3- oxo-2...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267392(5-fluoro-3-((1-((5-(4- fluorophenyl)-6-oxo- 1,6-di...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267394(3-chloro-5-((4-(1,1-difluoroethyl)-1-((5-(4-fluoro...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267396(3-chloro-5-((1-((6-(difluoromethyl)-3-oxo-2,3-dihy...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267398(3-((1-((6- (difluoromethyl)-3- oxo-2,3- dihydropyr...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267404(3-chloro-5-((4-(1,1- difluoroethyl)-1-((6- (1,1-di...)
Affinity DataIC50: 5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267228(3-chloro-5-((6-oxo-1-((3-oxo-2,3-dihydropyridazin-...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267268(3-chloro-5-((1-((5-(2- fluoro-4- methoxyphenyl)-6-...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267301(3-chloro-5-((1-((5-(6-fluoropyridin-3-yl)-6-oxo-1,...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267302(3-chloro-5-((1-((5-(2- methoxypyridin-4-yl)-6- oxo...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267309(3-chloro-5-((1-((5-(6- chloropyridin-3-yl)-6- oxo-...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267313(3-((1-((5-bromo-6-oxo- 1,6-dihydropyridazin-3- yl)...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267314(3-chloro-5-((1-((5-chloro-6-oxo-1,6-dihydropyridaz...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267315(3-chloro-5-((1-((5-(dimethylamino)-6-oxo-1,6-dihyd...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267337(3-chloro-5-((1-((6- (3-fluorophenyl)-3- oxo-2,3- d...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267341(3-chloro-5-((1-((6- cyclopropyl-3-oxo- 2,3- dihydr...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267346(4-(5-((5-(3-chloro- 5-cyanophenoxy)- 6-oxo-4- (tri...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267347(3-chloro-5-((1-((6- (4-chloro-3- fluorophenyl)-3- ...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267348(3-chloro-5-((6-oxo- 1-((3-oxo-6- (pyridin-3-yl)-2,...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267353(3-chloro-5-((1-((6-(1,1-difluoroethyl)-3-oxo-2,3-d...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
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TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267360(3-chloro-5-((6-oxo-1-((6-oxo-1,6-dihydropyrimidin-...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267391(3-(difluoromethoxy)- 5-((1-((5-(4- fluorophenyl)-6...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267397(3-chloro-5-((4- (difluoromethyl)-1-((6- (difluorom...)
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details
Go to US Patent

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