Compile Data Set for Download or QSAR
Report error Found 185 Enz. Inhib. hit(s) with all data for entry = 1850
TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344200((2R)-1-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344204((2R)-2-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344248(N-{6-[(3S)-4-acetyl-3-(methoxymethyl)piperazin-1-y...)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344282(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344241(N-{6-[(2S)-2-(hydroxymethyl)-4-(morpholin-4-ylcarb...)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344245(N-{6-[(2R)-4-acetyl-2-(hydroxymethyl)piperazin-1-y...)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344277(N-[6-(4-acetylpiperazin-1-yl)-2-methoxypyridin-3-y...)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344224(N-{6-[4-(N′-cyano-N-methylcarbamimidoyl)pipe...)
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344222(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344205(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344239(N-{6-[(3S)-4-acetyl-3-(hydroxymethyl)piperazin-1-y...)
Affinity DataIC50: 3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344279(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 3.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344290(N-[6-(1-acetylpiperidin-4-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 3.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344217(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344240(N-{6-[(2S)-4-acetyl-2-(hydroxymethyl)piperazin-1-y...)
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344264(N-[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]-6,6...)
Affinity DataIC50: 4.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344201(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344195(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344196(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344281(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344203(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 4.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344289(N-{6-(4-acetylpiperazin-1-yl)-2-[(1-oxidothietan-3...)
Affinity DataIC50: 4.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344285(N-[6-(4-acetylpiperazin-1-yl)-2-(oxetan-3-yloxy)py...)
Affinity DataIC50: 4.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344115(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 5.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344280(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344284(N-[6-(4-acetylpiperazin-1-yl)-2-(2,2,2-trifluoroet...)
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344190(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344223(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344234(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 5.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344274(5,5-dimethyl-N-(2-methyl-2H-indazol-5-yl)-4-oxo-4,...)
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344210(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344244(N-{6-[(3R)-4-acetyl-3-(hydroxymethyl)piperazin-1-y...)
Affinity DataIC50: 6.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344263(N-[2-methoxy-4-(piperazin-1-yl)phenyl]-6,6-dimethy...)
Affinity DataIC50: 6.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344291(US9777020, Example 185 | N-[6-(4-acetylpiperazin-1...)
Affinity DataIC50: 6.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344202((2S)-1-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Affinity DataIC50: 6.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344225(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 6.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344213(N-[2-(2-hydroxy-2-methylpropoxy)-6-(morpholin-4-yl...)
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344238(N-{2-isopropoxy-6-[(3aR,6aR)-1-[(4-methylpiperazin...)
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344197(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344220(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Affinity DataIC50: 7.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344251(6-ethoxy-5-({[5-(2-methoxyethyl)-6,6-dimethyl-4-ox...)
Affinity DataIC50: 7.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344221((6R) N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin...)
Affinity DataIC50: 8.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344242(N-{6-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-2-iso...)
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344287(N-{6-(4-acetylpiperazin-1-yl)-2-[(3S)-tetrahydrofu...)
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344265(N-(2-methyl-2H-indazol-5-yl)-4-oxo-4,7-dihydro-5H-...)
Affinity DataIC50: 10.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344246(N-{6-[bis(2-hydroxyethyl)amino]-2-isopropoxypyridi...)
Affinity DataIC50: 10.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344235(N-{6-[(3 aR,6aR)-hexahydropyrrolo[3,4-b]pyrrol-5(1...)
Affinity DataIC50: 10.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344286(N-[6-(4-acetylpiperazin-1-yl)-2-(tetrahydro-2H-pyr...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344229(N-{2-methoxy-6-[4-(pyrrolidin-1-ylcarbonyl)piperaz...)
Affinity DataIC50: 11.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344283(N-[6-(4-acetylpiperazin-1-yl)-2-(2-methoxyethoxyl)...)
Affinity DataIC50: 12.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
Go to US Patent

Displayed 1 to 50 (of 185 total ) | Next | Last >>
Jump to: