Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 1853
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344393((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl...)
Affinity DataIC50: 0.200nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344384((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperi...)
Affinity DataIC50: 7nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344388((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperi...)
Affinity DataIC50: 7.10nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344396((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(morpholin-4-yl...)
Affinity DataIC50: 12nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344379( (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-...)
Affinity DataIC50: 17nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344390((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-y...)
Affinity DataIC50: 20nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344397((E)-N1-(2-fluorophenyl)-N4-(3-fluoro-4-(6-methoxy-...)
Affinity DataIC50: 21nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344381( (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-y...)
Affinity DataIC50: 30nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344398((E)-N1-(3,5-dichlorophenyl)-N4-(3-fluoro-4-(6-meth...)
Affinity DataIC50: 110nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344383( (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-...)
Affinity DataIC50: 150nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344395((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(morpholin-4-yl...)
Affinity DataIC50: 200nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344380( (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiper...)
Affinity DataIC50: 200nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344385((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-y...)
Affinity DataIC50: 300nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344387((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-y...)
Affinity DataIC50: 350nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344394((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-y...)
Affinity DataIC50: 390nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344403((E)-N1-(3,5-difluorophenyl)-N4-(3-fluoro-4-(6-meth...)
Affinity DataIC50: 470nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344402((E)-N1-phenyl-N4-(3-fluoro-4-(6-methoxy-7-(3-(morp...)
Affinity DataIC50: 500nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344404((E)-N1-(3,5-dimethoxyphenyl)-N4-(3-fluoro-4-(6-met...)
Affinity DataIC50: 510nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344382( (E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-...)
Affinity DataIC50: 550nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344401((E)-N1-(4-chlorophenyl)-N4-(3-fluoro-4-(6-methoxy-...)
Affinity DataIC50: 580nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344400((E)-N1-phenyl-N4-(3-fluoro-4-(6-methoxy-7-(3-(4-me...)
Affinity DataIC50: 660nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344386((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(pyrrolidin-1-y...)
Affinity DataIC50: 670nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344399((E)-N1-(4-chloro-3-(trifluoromethyl)phenyl)-N4-(3-...)
Affinity DataIC50: 690nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344389((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(morpholin-4-yl...)
Affinity DataIC50: 710nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent