Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 2404
TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364365(US9861612, 2 | 4-[3-[2-chloro-6-(trifluoromethyl)b...)
Affinity DataIC50: 17.9nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364366(US9861612, 3 | 4-[3-[2-chloro-6-(trifluoromethyl)b...)
Affinity DataIC50: 37.9nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364366(US9861612, 3 | 4-[3-[2-chloro-6-(trifluoromethyl)b...)
Affinity DataIC50: 42.9nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364364(US9861612, 1 | US9861612, Comparator 1 | 4-[3-[2-c...)
Affinity DataIC50: 43.6nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364371(US9861612, Comparator 4 | 4-[3-[2-chloro-6-(triflu...)
Affinity DataIC50: 59.6nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364369(US9861612, Comparator 2 | 4-[7-fluoro-3-[2-fluoro-...)
Affinity DataIC50: 61.9nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364370(US9861612, Comparator 3 | 4-[3-(2,6-dichlorobenzoy...)
Affinity DataIC50: 91.6nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364364(US9861612, 1 | US9861612, Comparator 1 | 4-[3-[2-c...)
Affinity DataIC50: 97.4nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Orca Pharmaceuticals

US Patent
LigandPNGBDBM364372(US9861612, Comparator 5 | 3-fluoro-4-[7-fluoro-3-[...)
Affinity DataIC50: 111nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2019
Entry Details
US Patent