Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 3204
Target5-hydroxytryptamine receptor 1A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataIC50: 0.970nMAssay Description:Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataIC50: 0.980nMAssay Description:Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataIC50: 1.96nMAssay Description:Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataIC50: 2.25nMAssay Description:Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataIC50: 130nMAssay Description:Serotonin, 5HT2A :Materials and Methods: Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataIC50: 262nMAssay Description:Serotonin, 5HT2A :Materials and Methods: Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataKi:  0.300nMAssay Description:Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataKi:  0.610nMAssay Description:Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataKi:  0.650nMAssay Description:Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataKi:  1.5nMAssay Description:Serotonin, 5HT1A:Receptor Source: Human recombinant expressed in HEK-293 cellsRadioligand: [3H]-8-OH-DPAT (221 Ci/mmol)Control Compound: 8-OH-DPATInc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataKi:  58.5nMAssay Description:Serotonin, 5HT2A :Materials and Methods: Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataKi:  118nMAssay Description:Serotonin, 5HT2A :Materials and Methods: Receptor Source: Human Cortex Radioligand: [3H]-Ketanserin (60-90 Ci/mmol) Control Compound: Ketans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent