Compile Data Set for Download or QSAR
Report error Found 792 Enz. Inhib. hit(s) with all data for entry = 10419
TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534434BDBM534434(WO2022086828, Example 170)
Affinity DataIC50: 0.100nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534472BDBM534472(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.200nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534450BDBM534450(WO2022086828, Example 186)
Affinity DataIC50: 0.200nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534402BDBM534402(WO2022086828, Example 138)
Affinity DataIC50: 0.200nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534323BDBM534323(WO2022086828, Example 50)
Affinity DataIC50: 0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534328BDBM534328(WO2022086828, Example 55)
Affinity DataIC50: 0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534427BDBM534427(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534445BDBM534445(WO2022086828, Example 181)
Affinity DataIC50: 0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534325BDBM534325(WO2022086828, Example 52)
Affinity DataIC50: 0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534452BDBM534452(WO2022086828, Example 188)
Affinity DataIC50: 0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534440BDBM534440(WO2022086828, Example 176)
Affinity DataIC50: 0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534377BDBM534377(5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534424BDBM534424(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534432BDBM534432(WO2022086828, Example 168)
Affinity DataIC50: 0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534461BDBM534461(3 -(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-y...)
Affinity DataIC50: 0.300nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534443BDBM534443(WO2022086828, Example 179)
Affinity DataIC50: 0.300nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534579BDBM534579((S)-3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-...)
Affinity DataIC50: 0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534329BDBM534329(WO2022086828, Example 56)
Affinity DataIC50: 0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534447BDBM534447(WO2022086828, Example 183)
Affinity DataIC50: 0.400nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534380BDBM534380(5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534480BDBM534480(WO2022086828, Example 216)
Affinity DataIC50: 0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534288BDBM534288(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534448BDBM534448(WO2022086828, Example 184)
Affinity DataIC50: 0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534567BDBM534567(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.400nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534326BDBM534326(WO2018148626, Example 152 | WO2022086828, Example ...)
Affinity DataIC50: 0.5nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534547BDBM534547(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.5nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534562BDBM534562(3-(2-amino-[1,2,4]triazolo[1,5-α]pyri din-7-y...)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534326BDBM534326(WO2018148626, Example 152 | WO2022086828, Example ...)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534554BDBM534554(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.5nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534399BDBM534399(WO2022086828, Example 135)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534378BDBM534378(5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534497BDBM534497(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534379BDBM534379(5-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534302BDBM534302(WO2022086828, Example 30)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534554BDBM534554(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534358BDBM534358(WO2022086828, Example 85)
Affinity DataIC50: 0.5nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534410BDBM534410(WO2018148626, Example 146 | (S)-5-(2-amino-[1,2,4]...)
Affinity DataIC50: 0.600nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534341BDBM534341(WO2022086828, Example 68)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534342BDBM534342(WO2022086828, Example 69)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534564BDBM534564(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534497BDBM534497(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534471BDBM534471(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534404BDBM534404(WO2022086828, Example 140)
Affinity DataIC50: 0.600nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534285BDBM534285(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.600nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534569BDBM534569(WO2022086828, Example 305)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534275BDBM534275(WO2022086828, Example 3)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534410BDBM534410(WO2018148626, Example 146 | (S)-5-(2-amino-[1,2,4]...)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534419BDBM534419((S)-3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-...)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetMixed lineage kinase domain-like protein(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534449BDBM534449(WO2022086828, Example 185)
Affinity DataIC50: 0.600nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

WIPO
LigandChemical structure of BindingDB Monomer ID 534463BDBM534463(3-(2-amino-[1,2,4]triazolo[1,5-α]pyridin-7-yl...)
Affinity DataIC50: 0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022086828

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