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Found
97
Enz. Inhib. hit(s) with all data for entry = 13382
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784823
(N-(4-chloro-3-(cis-3-hydroxycyclobutyl)phenyl)-3-m...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784822
(N-(4-chloro-3-(trans-3-hydroxycyclobutyl)phenyl)-3...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784821
(N-(4-chloro-3-((1S,2R)-2-cyanocyclobutyl)-5-fluoro...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784820
(N-(4-chloro-3-((1R,2S)-2-cyanocyclobutyl)-5-fluoro...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784819
(N-(4-chloro-3-((1S,2R)-2-cyanocyclobutyl)phenyl)-3...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784818
(N-(4-chloro-3-((1R,2S)-2-cyanocyclobutyl)phenyl)-3...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784817
(N-(3-(trans-2-(4H-1,2,4-triazol-4-yl)cyclobutyl)-4...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784816
(N-(3-(cis-2-(2H-1,2,3-triazol-2-yl)cyclobutyl)-4-c...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784830
(N-(4-chloro-3-(cis-2-cyanocyclobutyl)phenyl)-3-(tr...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784829
(N-(4-chloro-3-(cis-3-hydroxycyclobutyl)phenyl)-3-(...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784828
(N-(4-chloro-3-(trans-3-hydroxycyclobutyl)phenyl)-3...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784826
(N-(4-chloro-3-((1R,2S)-2-(difluoromethyl)cyclobuty...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784825
(N-(4-chloro-3-(3-hydroxy-3-methylcyclobutyl)phenyl...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784824
(N-(4-chloro-3-(3-hydroxy-3-methylcyclobutyl)phenyl...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784806
(N-(3-(bicyclo[1.1.1]pentan-1-yl)-4-chlorophenyl)-3...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784805
(N-(4-chloro-3-(1-fluorocyclobutyl)phenyl)-3-methyl...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784804
(N-(4-chloro-3-cyclobutylphenyl)-3-methyl-6-azabicy...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784803
(N-(4-chloro-3-((1S,2R)-2-cyanocyclopropyl)phenyl)-...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784814
(N-(3-(cis-2-(1H-1,2,3-triazol-1-yl)cyclobutyl)-4-c...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784813
(N-(3-(trans-2-(1H-1,2,3-triazol-1-yl)cyclobutyl)-4...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784811
(WO2025054369, Example 25)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784810
(WO2025054369, Example 24)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784809
(WO2025054369, Example 23)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784854
((1S,3R,5R)-N-(4-chloro-3-cyclobutylphenyl)-1-(5-me...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784853
(N-(4-chloro-3-((1S,3R)-3-hydroxy-3-methylcyclopent...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784852
(N-(4-chloro-3-((1R,3S)-3-hydroxy-3-methylcyclopent...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784850
(N-(4-chloro-3-((1S,3S)-3-hydroxy-3-methylcyclopent...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784849
(N-(4-chloro-3-((1R,2R)-2-cyanocyclopentyl)phenyl)-...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784848
(N-(4-chloro-3-((1S,2S)-2-cyanocyclopentyl)phenyl)-...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784863
(WO2025054369, Example 77)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784862
(WO2025054369, Example 76)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784861
(WO2025054369, Example 75)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784860
(WO2025054369, Example 74)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784858
(N-(4-chloro-3-((S)-2-cyanoazetidin-1-yl)phenyl)-3-...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784857
(N-(4-chloro-3-((R)-2-cyanoazetidin-1-yl)phenyl)-3-...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784856
((1R,3S,5S)-N-(4-chloro-3-(3-hydroxyazetidin-1-yl)p...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784839
(N-(3-((1S,2R)-2-cyanocyclobutyl)-4-(trifluoromethy...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784837
(N-(4-chloro-3-((1R,2R)-2-(difluoromethyl)cyclobuty...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784836
(N-(4-chloro-3-((1S,2S)-2-(difluoromethyl)cyclobuty...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784835
(N-(4-chloro-3-(cis-3-fluorocyclobutyl)phenyl)-3-me...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784834
(N-(4-chloro-3-(trans-3-fluorocyclobutyl)phenyl)-3-...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784832
(N-(4-chloro-3-((1S,2S)-2-hydroxy-2-methylcyclobuty...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784847
(N-(4-chloro-3-((1S,2R)-2-cyanocyclopentyl)phenyl)-...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784846
(N-(4-chloro-3-((1R,2S)-2-cyanocyclopentyl)phenyl)-...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784843
(N-(4-chloro-3-((1S,2R)-2-cyanocyclobutyl)phenyl)-3...)
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Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
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Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784841
(N-(3-((1R,2R)-2-cyanocyclobutyl)-4-(trifluoromethy...)
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Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784840
(N-(3-((1S,2S)-2-cyanocyclobutyl)-4-(trifluoromethy...)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784882
(WO2025054369, Example 96)
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Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784881
(WO2025054369, Example 95)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
Target
NAD(+) hydrolase SARM1
(Human)
NICO Therapeutics
WIPO
Ligand
BDBM784870
(WO2025054369, Example 84)
Copy SMILES
Affinity Data
IC50: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369
Copy reaction URL
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