Reaction Details  Report a problem with these data
Cell Reactant:
Phospholipase C-γ1 SH2 domain (PLCC)
Syringe Reactant:
BDBM225241
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2017-05-11
ΔG°:
-52.8100±n/a (kJ/mole)
pH:
7.4000±0.0000
Log10Kb:
8
Temperature:
298.1500±0.0000 (K)
ΔH° :
-15.0000±0.4200 (kJ/mole)
ΔS° :
0.0694±0.0010 (kJ/mole-K)
Citation
 McKercher, MA; Guan, X; Tan, Z; Wuttke, DS Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-¿1 Protein. Biochemistry 56:2225-2237 (2017) [PubMed]  Article
Cell React
Name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [663-759]
Synonyms:
PLCG1_HUMAN | Phospholipase C-gamma-1 SH2 domain (PLCC) | PLC1 | PLCG1
Type:
Protein
Mol. Mass.:
11560.59
Organism:
Human
Description:
Human phospholipase C-gamma-1 C-terminal SH2 domain (663-759 aa)
Residue:
97
Sequence:
HESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE
  
Syringe React
Name:
BDBM225241
Synonyms:
MT-pep | 3-Nitro-N-(2-phenylbenzo[d]oxazol-6-yl)benzenesulfonamide (2)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: