| Assay Method Information | |
| | HDAC Inhibition Assay |
| Description: | These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic chain increases HDAC inhibition. As for the phenyl group, the presence of a relatively bulky substituent at the para position relative to the carbonyl group also affords potent HDAC inhibitors (Table 2). |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |