| Assay Method Information | |
| | PfPFT and Rat PFT IC50 Determination |
| Description: | Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were calculated using linear regression analysis of the plots of [3H] farnesyl pyrophosphate (FPP) prenylation versus concentration of compounds. |
| Affinity data for this assay | |
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