| Assay Method Information | |
| | FTase Scintillation Proximity Assay |
| Description: | Compounds were tested as inhibitors of FTase in vitro using purified human enzyme to catalyze the reaction between [3H] FPP and a biotinylated peptide substrate. Reaction was terminated by addition of streptavidin scintillation proximity assay beads (Amersham), and the mixtures were subsequently analyzed by scintillation counting. |
| Affinity data for this assay | |
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