| Assay Method Information | |
| | BACE Enzyme Inhibition Assay |
| Description: | Beta-cleavage ELISA assays were carried out in reaction buffer containing enzyme, substrate MBP-C125, and test compounds. Generated beta-cleaved product was detected using biotinylated Sw192 or biotinyated Wt192 as specific reporter antibodies and quantitated against the appropriate MBP-C125 standard. |
| Affinity data for this assay | |
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