| Assay Method Information | |
| | Radioligand Competition Assay |
| Description: | Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affinities for alpha 7 nAChR were determined in tissue preparation of rat cortical membranes using 1 nM [3H]alpha-bungarotoxin. Binding affinities for AChBP were determined by displacement of [3H]epibatidine to Ls-AChBP. |
| Affinity data for this assay | |
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