| Assay Method Information | |
| | ChEMBL_1715620 (CHEMBL4125669) |
| Description: | Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta secretion incubated for 1 hr prior to stimulation with nigericin for 1 hr by quanti-blue based SEAP reporter gene assay |
| Affinity data for this assay | |
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