Assay Method Information | |
| ChEMBL_2378957 |
Description: | Inhibition of GST-tagged human KRAS G12C mutant expressed in Escherichia coli/His10-tagged human SOS1 catalytic domain expressed in Escherichia coli protein-protein interaction preincubated with KRAS for 2 mins followed by SOS1 addition and measured after 60 mins by HTRF based assay |
Affinity data for this assay | |
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