| Assay Method Information | |
| | ChEMBL_1929799 (CHEMBL4432975) |
| Description: | Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase A128T mutant expressed in Escherichia coli BL21(DE3) cells assessed as reduction in LEDGF/p75 independent 3' processing activity using 32P-labeled blunt ended 21-mer DNA as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr by HTRF assay |
| Affinity data for this assay | |
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