Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) for PDB: 9AS6
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  87.6nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  118nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  208nMAssay Description:Data from pone.0009019.s006.doc, supplement tables.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  360nMAssay Description:Displacement of [125I]DOI from rat 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  551nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]DOI radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  2.60E+3nMAssay Description:Tested for its ability to activate phospholipase c by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  4.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  5.50E+3nMAssay Description:Ability to displace [3H]ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  5.50E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi: >1.00E+4nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataEC50:  1.13E+4nMAssay Description:Activity at rat 5HT2A receptor assessed as 5-HT-stimulated IP3 accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  1.74E+4nMAssay Description:5-HT2A Receptor Radioligand Binding. Affinity of the test compounds for the 5-HT2A receptor was determined in radioligand binding experiments with [3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Oklahoma

LigandChemical structure of BindingDB Monomer ID 50059891BDBM50059891(3,4,5-trimethoxyphenylethylamine | 3,4,5-trimethox...)
Affinity DataKi:  1.74E+4nMAssay Description:The binding affinities of disclosed compounds at the ketanserin binding site of the 5-HT2A receptor were determined in radioligand binding experiment...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)