Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 9CLW
TargetFree fatty acid receptor 2(Human)
Ogeda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305974BDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human FFA2R expressed in CHOK1 cells assessed as induction of GTPgamma35S binding preincubated for 15 mins followed by GTPgamma35...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFree fatty acid receptor 2(Human)
Ogeda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305974BDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataEC50:  417nMAssay Description:Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFree fatty acid receptor 2(Human)
Ogeda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305974BDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataIC50: 700nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)