TargetHigh affinity nerve growth factor receptor(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 0.961nMAssay Description:Inhibition of human TRKA using poly[Glu:Tyr] (4:1) as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 ...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Human)
Center for Lymphoid Malignancies
Curated by ChEMBL
Center for Lymphoid Malignancies
Curated by ChEMBL
Affinity DataIC50: 1.41nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair

3D Structure (crystal)