Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 9E7R
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of agonist-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-stimulated intracellular calcium release preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-stimulated intracellular calcium release preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced ca2+ release preincubated for 15 mins measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced ca2+ release preincubated for 15 mins measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at protease-activated receptor 2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of endogenous trypsin-stimulated intracellular calcium release by Fluo-3 AM d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 9.60E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of trypsin-induced ca2+ release preincubated for 15 mins measured after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440868BDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of trypsin-induced ca2+ release preincubated for 15 mins measured after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)