Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) for PDB: 9OEM
TargetGlutamate receptor ionotropic, NMDA 1(Human)
University Hospital Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073922BDBM50073922({(S)-1-[(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50: 5nMAssay Description:Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]MDL-105519 bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  130nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at rat GluN1/GluN2B NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Institut De Recherches Servier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory activity to inhibit [3H]glycine binding to NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  360nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2B NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  990nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataEC50:  1.00E+3nMAssay Description:Partial agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of L-glutamate by two-electrod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Institut De Recherches Servier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18133BDBM18133(2-aminoacetic acid | [14C]Glycine | CHEMBL773 | Gl...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibitory concentration required to inhibit [3H]strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)